NeoExoma, NeoGenoma or NeoGenoma Omni?
The three tests investigate possible genetic causes, but analyze DNA with different scopes. Compare the options to understand which conversation to take to your doctor.
Side by side
Three options, different range levels.
The best strategy depends on the signs, the tests already carried out and the types of changes that need to be looked for.
| Appearance | NeoExoma | NeoGenoma | NeoGenoma Omni |
|---|---|---|---|
| What you analyze | Mainly the parts of genes used to make proteins | A larger area of DNA, including regions outside the exome | The genome with short and long reads analyzed in a complementary way |
| What can you add | Focuses research in regions with extensive clinical knowledge | Greater coverage and greater diagnostic potential than the exome | Higher portfolio resolution when both technologies are suitable for the case |
| Point of attention | It can leave out regions and changes that the genome can evaluate | Not every region is well read or understood, even with greater reach | The combination of technologies also has limits and may not find a cause |
| Family participation | It can be individual or include family members, depending on the option available | It can be individual or include family members, depending on the option available | Configuration and requirements need to be confirmed for ordering |
- NeoExoma
- AnalyzeMainly the parts of genes used to make proteins.
- You can addFocuses research on regions with extensive clinical knowledge.
- AttentionIt may leave out regions and changes that the genome can assess.
- NeoGenoma
- AnalyzeA larger area of DNA, including regions that lie outside the exome.
- You can addGreater scope and greater diagnostic potential than the exome.
- AttentionNot every region is well read or understood, even with greater reach.
- NeoGenoma Omni
- AnalyzeThe genome with short and long reads analyzed in a complementary way.
- You can addGreater portfolio resolution when both technologies are suitable for the case.
- AttentionThe combination of technologies also has limits and may not find a cause.
Important: A more extensive examination may increase the potential for finding a cause, but neither guarantees a diagnosis. A specific suspicion may require another method.
Analysis with family members
Family comparison can help interpret the result.
The configuration depends on the case and the availability of family members. Each participant separately authorizes the use of their sample and data.
- 01
Individual
Analyzes only the patient and relates findings to available clinical and family information.
- 02
Duo
It compares the patient with a biological family member and can clarify part of the inheritance.
- 03
Threesome
It generally includes the patient and two biological parents, which can help to study the origin of the changes found.
Know each test
See what each test analyzes before deciding.
The product pages detail what is analyzed, the options available, and the limits for each test.
Frequently asked questions
To compare safely.
Is genome always better than exome?
No. The genome is more comprehensive, but a specific suspicion may require a focused test or other technology. The choice depends on the case.
When can NeoGenoma Omni add information?
When repetitive regions, very similar to each other or complex structural changes may be relevant. The team assesses whether the two forms of reading are suitable for the request.
Is it mandatory to include parents in the test?
No. Individual analysis can be done when appropriate. Family samples can add information, but the configuration depends on the family and the case.
Can these examinations fail to find an answer?
Yes. A result without an identified explanation does not exclude all genetic causes nor does it mean that all possible changes have been evaluated.
What happens if the report contains a VUS?
A variant of uncertain significance does not confirm a diagnosis nor should it alone guide health decisions. When reported by NeoGenomica, it is included in the Infinity VUS follow-up.
Next step
Do you want to understand which option corresponds to your request?
Our team can explain the scope, available configurations, and test requirements of NeoGenomica.
For patients and families
Information for each stage of the journey.
Start with the topic that comes closest to your question.
